N-Acetyl Semax Amidate 30 mg – Peptide Hubs
N-Acetyl Semax Amidate is a chemically enhanced version of the Semax peptide, designed for improved bioavailability, receptor binding, and neurochemical modulation. This version includes N-acetylation and C-terminal amidation for increased resistance to enzymatic degradation and enhanced penetration across the blood-brain barrier. Peptide Hubs offers this 30 mg vial as a high-purity research peptide for cognition, neuroprotection, and recovery applications.
Mechanism of Action
N-Acetyl Semax Amidate stimulates neurotrophin expression (notably BDNF), enhances dopamine and serotonin metabolism, and regulates stress-adaptation pathways. Unlike traditional stimulants or antidepressants, it supports cognitive clarity, working memory, and mental endurance without habituation or withdrawal. See this NCBI article on Semax's neuroregulatory role for reference.
Primary Research Applications
- Memory retention and focus under cognitive stress
- Stroke recovery and cerebral blood flow improvement
- Depression, anxiety, and fatigue resistance models
- Traumatic brain injury and neuroinflammation studies
This enhanced variant is often stacked with N-Acetyl Selank Amidate to explore synergistic anxiolytic and cognition support. It's also paired with Humanin in neurodegeneration models or FOX04-DRI in senescence and age-related CNS studies. For neurotransmitter support, researchers include DSIP in circadian rhythm-based cognitive research.
Technical Details
Peptide Type
Modified Synthetic Heptapeptide
Peptide Sequence
Ac-Met-Glu-His-Phe-Pro-Gly-Pro-NHβ
Peptide Length
7 Amino-Acid Residues
Parent Sequence
Met-Glu-His-Phe-Pro-Gly-Pro (MEHFPGP)
Structural Origin
Semax / ACTH(4-7)-Derived Peptide
N-Terminal Modification
Acetylated (Ac-)
C-Terminal Modification
Amidated (-NHβ)
Molecular Formula
CββHβ
βNββOββS
Molecular Weight
854.97 g/mol
Research Status
Experimental / Limited Direct Research
Dosage & Usage Guidelines
- Dosage: 300–1000 mcg per day depending on protocol
- Administration: Intranasal or subcutaneous injection
- Cycle Duration: 2–4 weeks per neuroplasticity or recovery phase
Stacking Recommendations
- N-Acetyl Selank Amidate – for anxiolytic synergy
- Humanin – in neurodegenerative and aging studies
- FOX04-DRI – for senolytic research in CNS repair
- DSIP – for stress recovery and neurotransmitter support
Safety & Legal Information
N-Acetyl Semax Amidate is not FDA-approved and is sold strictly for research use only. It is well tolerated in animal and in vitro studies, with no hormonal suppression, hepatotoxicity, or water retention. For ongoing trials and published data, refer to ClinicalTrials.gov.
Shipping & Product Authenticity
USA Domestic
4–5 business days
International
13–15 business days
Order Processing
24–48 business hours
Tracking
Tracking number provided
Direct Supply & Discreet Delivery
This product is supplied through the official Peptide Hubs distribution chain and shipped in original manufacturer packaging. The outer shipping package remains discreet, with privacy-focused handling and no unnecessary external product details.
What to Expect
- β Orders are processed after payment confirmation
- β USA Domestic shipping is typically faster when local stock is selected
- β International orders include tracking, though update frequency may vary by destination
- β Multiple warehouses may result in separate shipments when applicable
Authenticity support: official Peptide Hubs presentation, batch-linked lab proof, and original packaging help reinforce product legitimacy and buyer confidence.
Verified Supply
For complete delivery details, tracking policy, and reshipment terms, please see our Shipping Info page.
Storage
Store the lyophilized powder at controlled room temperature (15–25°C) in a dry, dark place, away from direct light and moisture. The unopened vial should be kept in its original packaging to maintain stability.
After reconstitution, store the solution at 2–8°C and use within 14 days. Do not freeze. Discard any unused portion after the recommended storage period. Before use, inspect the solution and avoid use if it appears cloudy, discolored, or contains particulate matter, or if the vial or seal is compromised.
Keep out of reach of children. Follow proper handling and sterile injection practices during research use.
Proper storage conditions help maintain product stability and consistent performance across the product's shelf life.
Frequently Asked Questions
What is N-Acetyl Semax Amidate used for?
It is used in research for enhancing memory, supporting stroke recovery, boosting neuroplasticity, and modulating neurotransmitters like dopamine and serotonin.
How does it differ from regular Semax?
N-Acetyl Semax Amidate has modifications that increase its resistance to degradation, resulting in better bioavailability and prolonged effect in preclinical models.
Does Semax affect sleep or energy levels?
Semax promotes mental clarity and energy without acting as a stimulant. It does not negatively affect sleep or cause dependence.
Is N-Acetyl Semax Amidate legal in the USA?
Yes, it is legal to purchase and use for scientific research purposes only. It is not approved by the FDA for human or veterinary use.
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