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N-Acetyl Epithalon Amidate 20 mg
Peptide Hubs

N-Acetyl Epithalon Amidate 20 mg

Product Details Peptide Hubs
Active Substance N-Acetyl Epithalon Amidate Modified Epitalon analog
Strength 20 mg per vial
Package 1 × 2 mL vial 20 mg labeled content
Form Lyophilized powder
Research Class Peptide bioregulator analog Epitalon-derived tetrapeptide
Peptide Sequence Ac-AEDG-NH₂ Ac-Ala-Glu-Asp-Gly-NH₂
Terminal Modifications Acetylated & amidated N-terminal acetylation + C-terminal amidation
Research Status Experimental Limited direct research on the modified analog
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N-Acetyl Epithalon Amidate 20 mg – Peptide Hubs

N-Acetyl Epithalon Amidate is a chemically enhanced version of the original Epithalon peptide, designed to improve bioavailability, metabolic resistance, and absorption. Epithalon is widely studied for its role in telomerase activation, pineal gland regulation, and potential anti-aging effects. This 20 mg research-grade peptide is produced by Peptide Hubs using pharmaceutical-grade standards.

Mechanism of Action

Epithalon influences the pineal gland, where it stimulates melatonin production and telomerase activity. Its N-acetylated and amidated modifications protect the molecule from rapid degradation and increase its half-life. This allows greater systemic distribution and extended effects on circadian rhythm, DNA repair, and oxidative stress modulation. For background, review this NIH overview on peptide-based aging interventions.

Key Research Applications

  • Telomerase activation and telomere length maintenance
  • Pineal gland and melatonin-related circadian rhythm studies
  • Anti-aging and longevity-focused experimental protocols
  • Neuroprotection, immune regulation, and oxidative stress models

This enhanced analog is commonly stacked with GHK Basic for skin and DNA repair support, or with Humanin to explore synergy in mitochondrial and aging pathways. Other popular combinations include FOX04-DRI in senolytic models and DSIP to study circadian and sleep-related outcomes.

Technical Details

Peptide Type
Modified Synthetic Tetrapeptide
Peptide Sequence
Ac-Ala-Glu-Asp-Gly-NH₂
Peptide Length
4 Amino-Acid Residues
Parent Sequence
Ala-Glu-Asp-Gly (AEDG)
N-Terminal Modification
Acetylated (Ac-)
C-Terminal Modification
Amidated (-NH₂)
Calculated Molecular Formula
C₁₆H₂₅N₅O₉
Calculated Molecular Weight
431.40 g/mol
Research Status
Experimental / Limited Direct Research

Dosage & Usage Guidelines

  • Dosage: 5–20 mg per week, often divided into daily 1–2 mg doses
  • Administration: Subcutaneous injection preferred
  • Duration: 2–4 weeks in telomerase or aging studies

Stacking Recommendations

  • FOX04-DRI – for senolytic support in aging models
  • Humanin – for mitochondrial protection and lifespan extension synergy
  • DSIP – to explore effects on melatonin and circadian rhythm
  • Livagen – for DNA repair support during anti-aging research

Safety & Legal Status

N-Acetyl Epithalon Amidate is provided for research use only. It is not FDA-approved. It has shown no androgenic, estrogenic, or hepatotoxic effects in preclinical settings. For trial updates and data, see ClinicalTrials.gov.

Shipping & Product Authenticity

USA Domestic
4–5 business days
International
13–15 business days
Order Processing
24–48 business hours
Tracking
Tracking number provided
Direct Supply & Discreet Delivery

This product is supplied through the official Peptide Hubs distribution chain and shipped in original manufacturer packaging. The outer shipping package remains discreet, with privacy-focused handling and no unnecessary external product details.

What to Expect

  • ✔ Orders are processed after payment confirmation
  • ✔ USA Domestic shipping is typically faster when local stock is selected
  • ✔ International orders include tracking, though update frequency may vary by destination
  • ✔ Multiple warehouses may result in separate shipments when applicable
Authenticity support: official Peptide Hubs presentation, batch-linked lab proof, and original packaging help reinforce product legitimacy and buyer confidence.
Verified Supply

For complete delivery details, tracking policy, and reshipment terms, please see our Shipping Info page.

Storage

Store the lyophilized powder at controlled room temperature (15–25°C) in a dry, dark place, away from direct light and moisture. The unopened vial should be kept in its original packaging to maintain stability.

After reconstitution, store the solution at 2–8°C and use within 14 days. Do not freeze. Discard any unused portion after the recommended storage period. Before use, inspect the solution and avoid use if it appears cloudy, discolored, or contains particulate matter, or if the vial or seal is compromised.

Keep out of reach of children. Follow proper handling and sterile injection practices during research use.

Proper storage conditions help maintain product stability and consistent performance across the product's shelf life.

Frequently Asked Questions

What is N-Acetyl Epithalon Amidate used for in research?

This peptide is researched for its ability to activate telomerase, regulate melatonin, and support cellular longevity through pineal gland pathways.

How is it different from standard Epithalon?

N-Acetyl Epithalon Amidate is chemically modified to resist degradation, increasing half-life and enhancing systemic distribution in animal models.

Is this peptide studied in longevity and anti-aging protocols?

Yes. It is commonly used in telomere-focused research, aging modulation, and melatonin studies for circadian rhythm regulation.

Is N-Acetyl Epithalon Amidate FDA approved?

No. It is not FDA-approved for human or veterinary use. It is sold for scientific and laboratory research purposes only.

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