Peptide Hubs
N-ACETYL EPITHALON AMIDATE 20 MG
CLASSIFICATION: PINEAL PEPTIDE / EPITHALON ANALOG
ACTIVE SUBSTANCE: N-ACETYL EPITHALON AMIDATE
FORM: LYOPHILIZED POWDER (2 ML VIAL x 20 MG)
ACTIVE HALF-LIFE: APPROX. 6–8 HOURS
DOSAGE: 5–20 MG/WEEK (RESEARCH USE)
ACNE: NO
WATER RETENTION: NO
HIGH BLOOD PRESSURE (HBP): NO
HEPATOTOXICITY: NONE
AROMATIZATION: NO
MANUFACTURER: PEPTIDE HUBS
N-ACETYL EPITHALON AMIDATE 20 MG Detailed
N-Acetyl Epithalon Amidate 20 mg – Peptide Hubs
N-Acetyl Epithalon Amidate is a chemically enhanced version of the original Epithalon peptide, designed to improve bioavailability, metabolic resistance, and absorption. Epithalon is widely studied for its role in telomerase activation, pineal gland regulation, and potential anti-aging effects. This 20 mg research-grade peptide is produced by Peptide Hubs using pharmaceutical-grade standards.
Mechanism of Action
Epithalon influences the pineal gland, where it stimulates melatonin production and telomerase activity. Its N-acetylated and amidated modifications protect the molecule from rapid degradation and increase its half-life. This allows greater systemic distribution and extended effects on circadian rhythm, DNA repair, and oxidative stress modulation. For background, review this NIH overview on peptide-based aging interventions.
Key Research Applications
- Telomerase activation and telomere length maintenance
- Pineal gland and melatonin-related circadian rhythm studies
- Anti-aging and longevity-focused experimental protocols
- Neuroprotection, immune regulation, and oxidative stress models
This enhanced analog is commonly stacked with GHK Basic for skin and DNA repair support, or with Humanin to explore synergy in mitochondrial and aging pathways. Other popular combinations include FOX04-DRI in senolytic models and DSIP to study circadian and sleep-related outcomes.
Suggested Experimental Use
- Dosage: 5–20 mg per week, often divided into daily 1–2 mg doses
- Administration: Subcutaneous injection preferred
- Duration: 2–4 weeks in telomerase or aging studies
Stacking Recommendations
- FOX04-DRI – for senolytic support in aging models
- Humanin – for mitochondrial protection and lifespan extension synergy
- DSIP – to explore effects on melatonin and circadian rhythm
- Livagen – for DNA repair support during anti-aging research
Safety & Legal Status
N-Acetyl Epithalon Amidate is provided for research use only. It is not FDA-approved. It has shown no androgenic, estrogenic, or hepatotoxic effects in preclinical settings. For trial updates and data, see ClinicalTrials.gov.
Frequently Asked Questions
What is N-Acetyl Epithalon Amidate used for in research?
This peptide is researched for its ability to activate telomerase, regulate melatonin, and support cellular longevity through pineal gland pathways.
How is it different from standard Epithalon?
N-Acetyl Epithalon Amidate is chemically modified to resist degradation, increasing half-life and enhancing systemic distribution in animal models.
Is this peptide studied in longevity and anti-aging protocols?
Yes. It is commonly used in telomere-focused research, aging modulation, and melatonin studies for circadian rhythm regulation.
Is N-Acetyl Epithalon Amidate FDA approved?
No. It is not FDA-approved for human or veterinary use. It is sold for scientific and laboratory research purposes only.
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