LL-37 5 mg – Peptide Hubs
LL-37 is a naturally occurring antimicrobial peptide (AMP) that plays a vital role in the human innate immune system. As the only known human cathelicidin peptide, LL-37 is involved in bacterial, viral, and fungal defense as well as in tissue healing and inflammation modulation. Peptide Hubs provides high-purity LL-37 in a 5 mg lyophilized vial for use in immune, dermatological, and regenerative research.
Mechanism of Action
LL-37 acts by disrupting the membranes of pathogens through electrostatic interactions, leading to bacterial cell lysis. Beyond antimicrobial activity, LL-37 also influences chemotaxis, angiogenesis, and epithelial cell proliferation, making it relevant in wound healing and immune surveillance models. For more information, see this NIH article on LL-37 functions in immunity.
Research Applications
- Broad-spectrum antimicrobial activity studies
- Skin repair and chronic wound healing models
- Respiratory epithelial defense research (e.g., sinusitis, lung injury)
- Modulation of inflammatory cytokines and immune response
LL-37 is often co-researched with GHK Basic for epithelial and collagen regeneration, or Chonluten for respiratory inflammation studies. Some researchers explore combined protocols with L-Glutathione for oxidative defense, or B7-33 for tissue remodeling in fibrotic conditions.
Technical Details
Peptide Type
Human Cathelicidin Host-Defense Peptide
Peptide Sequence
LLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLVPRTES
Peptide Length
37 Amino-Acid Residues
Terminal Form
H-LLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLVPRTES-OH
Molecular Formula
Cβββ
HβββNββOβ
β
Molecular Weight
4493 g/mol
Peptide Family
Cathelicidin Antimicrobial Peptide
Structural Profile
Cationic Amphipathic Peptide
Dosage & Usage Guidelines
- Dosage: 100–500 mcg daily depending on study
- Administration: Subcutaneous or intradermal injection
- Cycle Duration: 1–4 weeks in immune or tissue repair models
Stacking Recommendations
- DSIP – for immune support during recovery and anti-inflammatory balance
- FOX04-DRI – in aging-related immunomodulatory pathways
- Cardiogen – for vascular healing under oxidative stress models
- Semaglutide – for studies involving immune-metabolic regulation
Safety & Legal Status
LL-37 is a synthetic peptide intended strictly for research use only and is not FDA-approved. It shows no toxicity, does not aromatize, and has no hormonal interaction. It is well tolerated in skin, immune, and epithelial models. For active trials and data, refer to ClinicalTrials.gov.
Shipping & Product Authenticity
USA Domestic
4–5 business days
International
13–15 business days
Order Processing
24–48 business hours
Tracking
Tracking number provided
Direct Supply & Discreet Delivery
This product is supplied through the official Peptide Hubs distribution chain and shipped in original manufacturer packaging. The outer shipping package remains discreet, with privacy-focused handling and no unnecessary external product details.
What to Expect
- β Orders are processed after payment confirmation
- β USA Domestic shipping is typically faster when local stock is selected
- β International orders include tracking, though update frequency may vary by destination
- β Multiple warehouses may result in separate shipments when applicable
Authenticity support: official Peptide Hubs presentation, batch-linked lab proof, and original packaging help reinforce product legitimacy and buyer confidence.
Verified Supply
For complete delivery details, tracking policy, and reshipment terms, please see our Shipping Info page.
Storage
Store the lyophilized powder at controlled room temperature (15–25°C) in a dry, dark place, away from direct light and moisture. The unopened vial should be kept in its original packaging to maintain stability.
After reconstitution, store the solution at 2–8°C and use within 14 days. Do not freeze. Discard any unused portion after the recommended storage period. Before use, inspect the solution and avoid use if it appears cloudy, discolored, or contains particulate matter, or if the vial or seal is compromised.
Keep out of reach of children. Follow proper handling and sterile injection practices during research use.
Proper storage conditions help maintain product stability and consistent performance across the product's shelf life.
Frequently Asked Questions
What is LL-37 used for in research?
LL-37 is researched for its antimicrobial properties, wound healing support, and immune system regulation in epithelial and inflammatory conditions.
Is LL-37 effective against viruses and bacteria?
Yes. LL-37 exhibits activity against bacteria, viruses, and fungi by disrupting cell membranes and enhancing immune signaling.
Can LL-37 be used in wound healing studies?
Yes. LL-37 promotes angiogenesis, epithelial cell migration, and immune modulation, making it useful in skin regeneration models.
Is LL-37 FDA-approved?
No. LL-37 is not FDA-approved and is sold for research purposes only in laboratory or preclinical settings.
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