Humanin 10 mg – Peptide Hubs
Humanin is a mitochondrial-derived peptide (MDP) composed of 24 amino acids, discovered in the brain and muscle tissue. It plays a vital role in cellular protection, oxidative stress regulation, and age-related decline mitigation. Humanin has gained attention in longevity and neurodegeneration research for its unique cytoprotective signaling properties. Peptide Hubs offers Humanin in a 10 mg lyophilized vial, manufactured to research-grade quality standards.
Mechanism of Action
Humanin binds to specific receptors such as FPRL1 and IL-6-type receptors, modulating intracellular stress responses and apoptosis. It protects neurons, muscle cells, and endothelial tissue from oxidative damage and inflammation. Studies also suggest it enhances insulin sensitivity and supports mitochondrial biogenesis. For foundational insights, refer to this NIH review on Humanin's role in mitochondrial signaling.
Primary Research Applications
- Neuroprotection and Alzheimer's disease models
- Cardiovascular aging and endothelial repair studies
- Mitochondrial dysfunction and cellular stress models
- Longevity and anti-aging protocols
Researchers exploring synergy often combine Humanin with GHK Basic for tissue regeneration or DSIP for cognitive and sleep-related studies. When investigating senolytic or aging interventions, it may also complement FOX04-DRI or GHRP-2 in mitochondrial restoration protocols.
Technical Details
Peptide Type
Mitochondrial-Derived Peptide
Peptide Sequence
MAPRGFSCLLLLTSEIDLPVKRRA
Peptide Length
24 Amino Acids
Molecular Formula
CβββHβββNββOββSβ
Molecular Weight
2687.3 g/mol
Genetic Origin
Mitochondrial 16S rRNA Region
Research Profile
Cytoprotective Signaling
Research Status
Experimental / Preclinical
Dosage & Usage Guidelines
Suggested Experimental Use
- Dosage: 1–10 mg weekly, divided across several micro-doses
- Administration: Subcutaneous or intraperitoneal injection
- Duration: 2–12 weeks depending on the research model
Stacking Options
- FOX04-DRI – for mitochondrial senescence-clearing studies
- Chonluten – for immune-cognitive modulation under aging conditions
- B7-33 – to explore fibrosis reduction and vascular remodeling
- Cardiogen – for myocardial repair and oxidative stress reduction
Safety & Legal Status
Humanin is not FDA-approved and is strictly for laboratory research use only. It has demonstrated a favorable safety profile in preclinical models with no reported toxicity, androgenic activity, or hormonal interference. Humanin does not aromatize or elevate prolactin levels. For the latest trials and molecular pathways, consult ClinicalTrials.gov.
Shipping & Product Authenticity
USA Domestic
4–5 business days
International
13–15 business days
Order Processing
24–48 business hours
Tracking
Tracking number provided
Direct Supply & Discreet Delivery
This product is supplied through the official Peptide Hubs distribution chain and shipped in original manufacturer packaging. The outer shipping package remains discreet, with privacy-focused handling and no unnecessary external product details.
What to Expect
- β Orders are processed after payment confirmation
- β USA Domestic shipping is typically faster when local stock is selected
- β International orders include tracking, though update frequency may vary by destination
- β Multiple warehouses may result in separate shipments when applicable
Authenticity support: official Peptide Hubs presentation, batch-linked lab proof, and original packaging help reinforce product legitimacy and buyer confidence.
Verified Supply
For complete delivery details, tracking policy, and reshipment terms, please see our Shipping Info page.
Storage
Store the lyophilized powder at controlled room temperature (15–25°C) in a dry, dark place, away from direct light and moisture. The unopened vial should be kept in its original packaging to maintain stability.
After reconstitution, store the solution at 2–8°C and use within 14 days. Do not freeze. Discard any unused portion after the recommended storage period. Before use, inspect the solution and avoid use if it appears cloudy, discolored, or contains particulate matter, or if the vial or seal is compromised.
Keep out of reach of children. Follow proper handling and sterile injection practices during research use.
Proper storage conditions help maintain product stability and consistent performance across the product's shelf life.
Frequently Asked Questions
What is Humanin used for in research?
Humanin is studied for its role in neuroprotection, anti-aging, mitochondrial signaling, and resistance to oxidative stress and apoptosis.
Is Humanin a natural peptide?
Yes. Humanin is a naturally occurring mitochondrial-derived peptide first discovered in human brain tissue and shown to protect cells from degeneration.
How is Humanin different from FOX04-DRI?
While both have anti-aging properties, Humanin protects mitochondria and supports metabolic health, whereas FOX04-DRI targets cellular senescence directly.
Can Humanin be stacked with other peptides?
Yes. Humanin is frequently stacked with GHK Basic, DSIP, or FOX04-DRI in research focused on tissue repair, cognitive function, and longevity enhancement.
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