 
 
 
 
CLASSIFICATION: GROWTH HORMONE RELEASING HORMONE ANALOG
 ACTIVE SUBSTANCE: MODIFIED GRF 1-29
 FORM: LYOPHILIZED POWDER (2 ML VIAL x 5 MG)
 ACTIVE HALF-LIFE: APPROXIMATELY 30 MINUTES
 DOSAGE: 100-300 MCG 1-3 TIMES DAILY
 ACNE: RARE
 WATER RETENTION: LOW
 HIGH BLOOD PRESSURE (HBP): UNLIKELY
 HEPATOTOXICITY: NONE REPORTED
 AROMATIZATION: DOES NOT CONVERT TO ESTROGEN
 MANUFACTURER: PEPTIDE HUBS
LABORATORY TESTED: VIEW LAB RESULTS
Experience the power of precise growth hormone stimulation with Peptide Hubs' CJC-1295 No DAC 5mg. This advanced peptide, also known as Modified GRF 1-29, represents the cutting edge of growth hormone-releasing hormone (GHRH) analogs. Unlike its DAC-bound counterpart, CJC-1295 No DAC provides rapid, pulsatile growth hormone release that closely mimics the body's natural secretion patterns without extended activity.
CJC-1295 No DAC is a modified version of the native Growth Hormone-Releasing Hormone (GHRH) fragment comprising the first 29 amino acids. The modification includes the replacement of the second amino acid (alanine) with aspartic acid, significantly enhancing stability and bioavailability while maintaining full biological activity. This precise modification creates a peptide resistant to dipeptidyl peptidase IV degradation, extending its half-life compared to the native GHRH (1-29) while preserving the natural pulsatile release pattern.
According to research published in the National Institutes of Health, GHRH analogs like Modified GRF 1-29 stimulate growth hormone secretion through specific pituitary receptors, activating the cAMP pathway and ultimately increasing both GH production and release. This mechanism produces a physiological pulse pattern that differs from the non-pulsatile, sustained elevation seen with long-acting GHRH analogs or exogenous growth hormone administration.
Mimics the body's natural growth hormone secretion pattern for physiological results with minimal side effects.
Promotes lipolysis and reduces adipose tissue, particularly stubborn abdominal fat, without catabolic effects.
Accelerates recovery between training sessions through enhanced protein synthesis and cellular repair.
When administered before bedtime, increases deep sleep phases and maximizes natural nocturnal GH pulses.
For those seeking complementary peptides, consider our GHRP-2 which offers powerful growth hormone releasing effects through a different mechanism of action.
Reconstitute the lyophilized powder with bacteriostatic water before administration. The typical dosage ranges from 100-300 mcg, administered 1-3 times daily. Due to its short half-life (approximately 30 minutes), timing is crucial for optimal results. Most users experience best outcomes with administration on an empty stomach—upon waking, pre-workout, and especially before bedtime to coincide with the body's natural nocturnal growth hormone surge. Avoid administering immediately after meals as elevated blood glucose can blunt the growth hormone response.
For optimal results, consider pairing with our Sterile Bacteriostatic Water (10ml) which provides the ideal solvent for peptide reconstitution and preservation.
Typical cycles range from 8-12 weeks, followed by a 4-week break to prevent receptor desensitization. Most users report noticeable improvements in recovery and sleep quality within the first 1-2 weeks, with visible body composition changes becoming apparent within 4-6 weeks. For enhanced results, CJC-1295 No DAC can be effectively stacked with growth hormone secretagogues (GHSs) that work through different mechanisms.
Consider combining with Ipamorelin for a powerful growth hormone-releasing combination that mimics natural secretion patterns, or with Mechano Growth Factor (MGF) for targeted muscle repair and localized growth stimulation.
Important: This product is intended for research purposes only. Not for human consumption. Always consult with a healthcare professional before beginning any new supplement regimen.
Our CJC-1295 No DAC undergoes rigorous third-party testing to ensure >99% purity, accurate peptide sequencing, and complete sterility. Each batch is manufactured in ISO-certified facilities using pharmaceutical-grade ingredients and advanced lyophilization technology. The result is a premium peptide product that delivers consistent, measurable results for serious athletes and researchers.

For those interested in other research compounds, explore our Epitalon for telomere support and cellular health, or our LL-37 for immune system modulation and antimicrobial research.
Peptide Hubs remains committed to providing the highest quality research peptides to the scientific community. Our CJC-1295 No DAC represents the pinnacle of peptide technology, offering researchers a precise tool for studying growth hormone dynamics without the extended activity profile of DAC-modified analogs.
The primary difference lies in their half-lives and release profiles. CJC-1295 with DAC (Drug Affinity Complex) binds to albumin in the bloodstream, extending its half-life to approximately 7-10 days and creating sustained GH release. CJC-1295 No DAC (Modified GRF 1-29) has a short half-life of about 30 minutes, producing brief, pulsatile GH releases that closely mimic the body's natural secretion pattern. The No DAC version allows for more precise timing of GH pulses and avoids the continuous elevation seen with the DAC version.
The most effective administration times are on an empty stomach—typically upon waking, pre-workout, and especially before bedtime. The pre-bedtime administration is particularly important as it coincides with the body's natural nocturnal growth hormone surge. Avoid administering immediately after meals (wait 2-3 hours post-meal) as elevated blood glucose and insulin levels can blunt the growth hormone response. Due to its short half-life, timing is more critical with CJC-1295 No DAC than with longer-acting peptides.
Yes, CJC-1295 No DAC is frequently and effectively combined with growth hormone secretagogues (GHSs) like GHRP-6, GHRP-2, or Ipamorelin. These combinations create a synergistic effect as they work through different mechanisms—CJC-1295 No DAC stimulates GH release through GHRH receptors, while GHSs work through ghrelin receptors. This dual approach often produces a greater GH release than either compound alone. Many users report excellent results with a 100-300 mcg dose of each peptide administered simultaneously.
Users typically notice improved sleep quality and enhanced recovery within the first 1-2 weeks. Visible fat loss, especially around the abdominal area, becomes apparent within 4-6 weeks. Full cycle results include significantly improved muscle definition, reduced body fat, enhanced recovery between workouts, improved skin texture and elasticity, and increased lean muscle mass. The pulsatile nature of CJC-1295 No DAC means it produces more natural, physiological results compared to sustained-release compounds.
CJC-1295 No DAC is generally well-tolerated with an excellent safety profile. Some users report temporary flushing, lightheadedness, or tingling sensations shortly after injection—these typically subside within 30 minutes. Unlike traditional GH therapy or long-acting GHRH analogs, CJC-1295 No DAC does not cause water retention, joint pain, or carpal tunnel syndrome due to its pulsatile release pattern. The modified structure also reduces potential histamine responses compared to some other peptides.
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CLASSIFICATION: GROWTH HORMONE RELEASING HORMONE
 ACTIVE SUBSTANCE: CJC-1295 DAC
 FORM: 2 ML VIAL x 5 MG (LYOPHILIZED POWDER)
 ACTIVE HALF-LIFE: ~ 6-8 days
 DOSAGE: 500 - 1000 MCG, 2-3X PER WEEK
 ACNE: RARE
 WATER RETENTION: MINIMAL
 HIGH BLOOD PRESSURE (HBP): NO
 HEPATOTOXICITY: NONE
 AROMATIZATION: NONE
 MANUFACTURER: DRAGON PHARMA
 
CLASSIFICATION: RECOMBINANT HUMAN GROWTH HORMONE (rHGH)
 ACTIVE SUBSTANCE: SOMATROPIN
 FORM: 1 PRE-FILLED PEN x 36 IU (12 MG)
 ACTIVE HALF-LIFE: ~3.5 HOURS (SUBQ)
 DOSAGE: 1–4 IU/DAY FOR ANTI-AGING; 4–8 IU/DAY FOR FAT LOSS OR PERFORMANCE
 WATER RETENTION: POSSIBLE (DOSE DEPENDENT)
 HEPATOTOXICITY: NONE
 AROMATIZATION: NO
 MANUFACTURER: PFIZER
 
CLASSIFICATION: RECOMBINANT HUMAN GROWTH HORMONE (r-hGH)
 ACTIVE SUBSTANCE: SOMATROPIN (R-HGH)
 FORM: 1 CARTRIDGE x 15 MG 
 ACTIVE HALF-LIFE: ~2–3 HOURS
 DOSAGE: MEN 4-10 IU/DAY
 ACNE: POSSIBLE
 WATER RETENTION: POSSIBLE
 HIGH BLOOD PRESSURE (HBP): MAY INCREASE VIA FLUID RETENTION
 HEPATOTOXICITY: NONE TYPICAL
 AROMATIZATION: NONE
 MANUFACTURER: NOVO NORDISK
 
CLASSIFICATION: GONADOTROPIN (LH RECEPTOR AGONIST)
 ACTIVE SUBSTANCE: HUMAN CHORIONIC GONADOTROPIN
 FORM: 1 LYOPHILIZED VIAL x 5000 IU + PROVIDED SOLVENT
 ACTIVE HALF-LIFE: ~24–36 HOURS
 DOSAGE: MEN 500-1000 IU
 ACNE: POSSIBLE
 WATER RETENTION: POSSIBLE
 HIGH BLOOD PRESSURE (HBP): MONITOR IF AT CV RISK
 HEPATOTOXICITY: NONE TYPICAL
 AROMATIZATION: INDIRECT
 MANUFACTURER: IBSA
 
CLASSIFICATION: PEPTIDE HORMONE / HCG
 ACTIVE SUBSTANCE: HUMAN CHORIONIC GONADOTROPIN
 FORM: 1 ML AMP x 5000 IU
 ACTIVE HALF-LIFE: ~3–6 DAYS
 DOSAGE: 250–1000 IU 2–3x/WEEK (ON-CYCLE or PCT)
 ACNE: POSSIBLE
 WATER RETENTION: MODERATE
 HIGH BLOOD PRESSURE (HBP): UNLIKELY
 HEPATOTOXICITY: NONE
 AROMATIZATION: INDIRECTLY ELEVATES ESTROGEN
 MANUFACTURER: SUN PHARMA