Peptides
P21 5 mg
Product Details Dragon Pharma
Active Substance P21 P021
Strength 5 mg per vial
Package 1 vial 2 mL lyophilized powder
Form Lyophilized Powder
Vial Size 2 mL
Reconstitution Bacteriostatic water required
Source CNTF-derived tetrapeptide
Primary Research Neurogenesis & BDNF
Out of stock
Dragon Pharma P21 5 mg – Synthetic CNTF-Derived Peptide for Neurogenesis Research
✔ Synthetic lipophilic tetrapeptide ✔ Derived from ciliary neurotrophic factor (CNTF) ✔ Blood-brain barrier penetrant ✔ USA domestic shipping available
Dragon Pharma P21 5 mg is a synthetic, lipophilic tetrapeptide derived from ciliary neurotrophic factor (CNTF). This compound, also known as P021, has been designed to cross the blood-brain barrier and is studied in preclinical models for its potential to promote neurogenesis, increase brain-derived neurotrophic factor (BDNF) levels, and support synaptic plasticity in the context of neurodegenerative conditions such as Alzheimer's disease.
Each vial contains 5 mg of lyophilized P21 in a 2 mL format, requiring reconstitution with bacteriostatic water before use. The unique lipophilic properties of P21 enable effective CNS penetration, making it a valuable tool for investigating neuroregenerative mechanisms and cognitive function in research settings. For related research compounds, explore our peptides category and specifically Semax for complementary neuropeptide research applications.
What Makes P21 Valuable in Research?
P21 represents a focused approach to studying neurotrophic signaling and neurogenesis. By mimicking key functional domains of CNTF while maintaining a small, lipophilic structure, this peptide offers improved CNS bioavailability compared to larger neurotrophic factors. Its ability to enhance BDNF expression and support synaptic plasticity provides researchers with a tool to investigate the molecular pathways underlying learning, memory, and neural repair.
Researchers value P21 for its targeted mechanism and practical research applications. Its small size and blood-brain barrier penetration capabilities make it suitable for various experimental designs, from in vitro neuronal culture studies to in vivo models of cognitive function and neurodegeneration. For investigators exploring other neuroprotective compounds, DIHEXA 5 mg offers complementary research avenues in synaptic enhancement and cognitive function.
Current scientific literature on P21 and related neurotrophic peptides can be accessed through the PubMed database, where researchers can review peer-reviewed studies on its biological activity and experimental applications.
Key Research Applications for Dragon Pharma P21
- ✔ Investigation of neurogenesis and neural stem cell differentiation
- ✔ Evaluation of BDNF expression and signaling pathways
- ✔ Research on synaptic plasticity and cognitive function
- ✔ Studies of neurodegenerative disease models
- ✔ Preclinical models of learning and memory enhancement
For Research Purposes Only
P21 5 mg is intended for research use only and is not approved for human consumption. Proper handling, reconstitution, and experimental protocols are essential for reliable results. For studies on neural repair mechanisms, BPC 157 provides additional research avenues in tissue protection and recovery.
Technical Details
Compound Type
CNTF-Derived Peptidergic Compound
Structural Sequence
Ac-DGGLAG-NH₂
CNTF-Derived Region
Asp-Gly-Gly-Leu (DGGL)
Structural Modification
C-Terminal Adamantylated Glycine
Molecular Formula
C₂₇H₄₂N₆O₈
Molecular Weight
578.7 g/mol
CAS Number
1246751-68-7
PubChem CID
56589645
Parent Protein
Ciliary Neurotrophic Factor (CNTF)
Research Status
Experimental / Preclinical
Dosage & Usage Guidelines
For research and laboratory use only. Dragon Pharma P21 5 mg is a synthetic lipophilic tetrapeptide. Proper reconstitution, handling, and experimental design are essential for obtaining reliable data.
Reconstitution Protocol
- ✔ Use sterile bacteriostatic water for injection
- ✔ Add appropriate volume to achieve desired concentration
- ✔ Swirl gently to dissolve – do not shake vigorously
- ✔ Store reconstituted solution at 2–8°C
Reconstitute the lyophilized powder using bacteriostatic water to a concentration suitable for your research protocol. The 5 mg format allows for precise dosing across a range of experimental models. Always use aseptic technique during preparation to maintain peptide integrity.
Typical Research Parameters
In research settings, P21 is typically administered via subcutaneous or intraperitoneal injection. Dosing schedules and concentrations vary widely depending on the experimental design, animal model, and specific research objectives.
- ✔ Commonly used in neurogenesis and cognitive function studies
- ✔ Often combined with behavioral and molecular analysis
- ✔ Used to investigate BDNF expression and synaptic plasticity
- ✔ Research models include neurodegeneration and cognitive impairment paradigms
Factors to Consider in Research Protocols
- Lipophilic properties facilitate blood-brain barrier penetration
- Reconstitution stability is limited; prepare fresh solutions for each use
- Individual variation in response may be observed across subjects
- Storage conditions significantly impact peptide stability
Research note: P21 is derived from CNTF and designed to cross the blood-brain barrier. Its ability to promote neurogenesis and increase BDNF expression makes it a valuable tool for investigating neural plasticity, cognitive function, and potential therapeutic approaches in neurodegenerative disease research.
Lab Testing & Batch Transparency
Third-party analytical testing (COA) for Dragon Pharma P21 5 mg is currently not yet available. Batch-specific assay data, purity analysis, and verification documentation will be published once released.
Testing Status
Pending
COA Availability
Not yet published
Batch Verification
In progress
Update
Coming soon
Transparency note: Dragon Pharma publishes batch-specific lab reports once analytical testing is completed and verified.
Awaiting COA
Shipping & Product Authenticity
USA Domestic
4–5 business days
International
13–15 business days
Order Processing
24–48 business hours
Tracking
Tracking number provided
Direct Supply & Discreet Delivery
This product is supplied through the official Dragon Pharma distribution chain and shipped in original manufacturer packaging. The outer shipping package remains discreet, with privacy-focused handling and no unnecessary external product details.
What to Expect
- ✔ Orders are processed after payment confirmation
- ✔ USA Domestic shipping is typically faster when local stock is selected
- ✔ International orders include tracking, though update frequency may vary by destination
- ✔ Multiple warehouses may result in separate shipments when applicable
Authenticity support: official Dragon Pharma presentation, batch-linked lab proof, and original packaging help reinforce product legitimacy and buyer confidence.
Verified Supply
For complete delivery details, tracking policy, and reshipment terms, please see our Shipping Info page.
Storage
Store the lyophilized powder at controlled room temperature (15–25°C) in a dry, dark place, away from direct light and moisture. The unopened vial should be kept in its original packaging to maintain stability.
After reconstitution, store the solution at 2–8°C and use within 14 days. Do not freeze. Discard any unused portion after the recommended storage period. Before use, inspect the solution and avoid use if it appears cloudy, discolored, or contains particulate matter, or if the vial or seal is compromised.
Keep out of reach of children. Follow proper handling and sterile injection practices during research use.
Proper storage conditions help maintain product stability and consistent performance across the product's shelf life.
Frequently Asked Questions
What is Dragon Pharma P21 5 mg used for?
P21 is used in research to investigate neurogenesis, BDNF expression, and synaptic plasticity. It is a synthetic lipophilic tetrapeptide derived from CNTF, designed to cross the blood-brain barrier for neuroscience research applications.
What is the source of P21?
P21 is a synthetic tetrapeptide derived from ciliary neurotrophic factor (CNTF). Its lipophilic properties enable effective blood-brain barrier penetration, making it valuable for CNS research.
How do I reconstitute P21 5 mg powder?
Reconstitute the lyophilized powder with sterile bacteriostatic water for injection. Add the appropriate volume, swirl gently until fully dissolved, and avoid vigorous shaking to preserve peptide integrity.
What is the shelf life of P21 after reconstitution?
Reconstituted P21 should be stored at 2–8°C and used within 14 days. Discard any unused solution after this period to ensure stability and research accuracy.
Is Dragon Pharma P21 5 mg lab-tested?
Third-party laboratory testing for P21 5 mg is currently pending. Batch-specific COA data will be published once analytical testing is completed and verified.
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