SS-31 50 mg SS-31 50 mg
Peptide Hubs

SS-31 50 mg

Product Details Peptide Hubs
Active Substance Elamipretide SS-31 · MTP-131
Strength 50 mg/vial
Vial Size 2 mL vial
Form Lyophilized powder For reconstitution
Research Class Mitochondrial peptide
Peptide Length 4 amino acids Tetrapeptide
Human Half-Life Not established For this formulation
Primary Target Cardiolipin Inner mitochondrial membrane
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SS-31 50 mg – Mitochondria-Targeting Peptide for Research | Peptide Hubs

SS-31 (also known as Elamipretide) is a mitochondria-targeted tetrapeptide investigated for its unique ability to preserve and restore mitochondrial function. Peptide Hubs offers this powerful compound in a 50 mg (2 mL) vial, designed for laboratory use in studies focused on cellular energy, oxidative damage, neurodegeneration, and age-related tissue decline.

What is SS-31?

SS-31 is a synthetic peptide (D-Arg-dimethylTyr-Lys-Phe-NH2) that penetrates mitochondria and binds to cardiolipin, a lipid critical for mitochondrial integrity. Its primary mechanism involves reducing mitochondrial ROS (reactive oxygen species) while enhancing ATP production. In preclinical studies, SS-31 has demonstrated potential in improving cardiac, muscular, neural, and renal function.

According to recent findings published in PubMed, SS-31 may reduce age-related decline and organ dysfunction by enhancing mitochondrial bioenergetics and minimizing oxidative stress in critical tissues.

Potential Research Applications

  • Neurodegeneration (e.g., Parkinson's, Alzheimer's models)
  • Age-related macular degeneration (AMD)
  • Heart failure and myocardial ischemia models
  • Renal protection during acute kidney injury
  • Muscular atrophy, fatigue, and mitochondrial myopathy

Technical Details

Peptide Type
Aromatic-Cationic Tetrapeptide
Peptide Sequence
D-Arg-Dmt-Lys-Phe-NH₂
Peptide Length
4 Amino-Acid Residues
Structural Features
D-Arg + 2,6-Dimethyltyrosine (Dmt)
Terminal Form
C-Terminal Amide (-NH₂)
Molecular Formula
C₃₂H₄₉N₉O₅
Molecular Weight
639.8 g/mol
CAS Number
736992-21-5
PubChem CID
11764719
Molecular Target
Cardiolipin
Target Location
Inner Mitochondrial Membrane
Alternative Names
SS-31 / MTP-131 / Bendavia

Dosage & Usage Guidelines

In experimental settings, SS-31 is typically dosed between 10 mg to 25 mg per week, administered subcutaneously or intraperitoneally in animal models. Its effects have been observed even with short-term protocols of 7–14 days, depending on the research focus. It is important to use sterile, research-grade solvents during reconstitution for optimal performance.

Stacking Options for Advanced Studies

SS-31 is frequently stacked with other cellular repair peptides to expand therapeutic targets:

  • BPC-157 – promotes tissue repair and reduces inflammation
  • GHK-Cu – for regenerative and anti-aging research
  • AOD-9604 – for fat metabolism and metabolic protection
  • Thymosin Beta-4 – for angiogenesis and cardiovascular protection

Safety Profile and Side Effects (in Research Models)

SS-31 has shown excellent tolerability in preclinical and early human studies. No hormonal, hepatic, or renal toxicity has been reported in existing data. It does not affect androgenic or estrogenic pathways. Transient redness or mild irritation at the injection site may occur but resolves quickly with proper handling.

USA Domestic Shipping – Trusted Quality from Peptide Hubs

Peptide Hubs ensures fast USA domestic shipping of SS-31 50 mg and all peptide products. Each vial is manufactured under strict GMP standards and labeled for research use only. Explore related products like CJC-1295 DAC or Ipamorelin for complete anti-aging and metabolic study solutions.

Shipping & Product Authenticity

USA Domestic
4–5 business days
International
13–15 business days
Order Processing
24–48 business hours
Tracking
Tracking number provided
Direct Supply & Discreet Delivery

This product is supplied through the official Peptide Hubs distribution chain and shipped in original manufacturer packaging. The outer shipping package remains discreet, with privacy-focused handling and no unnecessary external product details.

What to Expect

  • ✔ Orders are processed after payment confirmation
  • ✔ USA Domestic shipping is typically faster when local stock is selected
  • ✔ International orders include tracking, though update frequency may vary by destination
  • ✔ Multiple warehouses may result in separate shipments when applicable
Authenticity support: official Peptide Hubs presentation, batch-linked lab proof, and original packaging help reinforce product legitimacy and buyer confidence.
Verified Supply

For complete delivery details, tracking policy, and reshipment terms, please see our Shipping Info page.

Storage

Store the lyophilized powder at controlled room temperature (15–25°C) in a dry, dark place, away from direct light and moisture. The unopened vial should be kept in its original packaging to maintain stability.

After reconstitution, store the solution at 2–8°C and use within 14 days. Do not freeze. Discard any unused portion after the recommended storage period. Before use, inspect the solution and avoid use if it appears cloudy, discolored, or contains particulate matter, or if the vial or seal is compromised.

Keep out of reach of children. Follow proper handling and sterile injection practices during research use.

Proper storage conditions help maintain product stability and consistent performance across the product's shelf life.

Frequently Asked Questions

What is SS-31 used for in research?

SS-31 is studied for its ability to protect and restore mitochondrial function, improve energy production, and reduce oxidative damage in organ systems.

Is SS-31 safe for research animals?

Yes, studies have shown that SS-31 has a strong safety profile with no major side effects when used correctly in preclinical models.

How should SS-31 be administered in a lab setting?

It is typically administered via subcutaneous or intraperitoneal injection, depending on the design of the research study.

Can SS-31 be stacked with other peptides?

Yes, it is often stacked with BPC-157, GHK-Cu, or CJC-1295 DAC to expand the benefits of mitochondrial repair, tissue regeneration, and aging research.

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