Peptide Hubs
KISSPEPTIN-10 5 MG
CLASSIFICATION: GNRH SECRETAGOGUE PEPTIDE
ACTIVE SUBSTANCE: KISSPEPTIN-10
FORM: LYOPHILIZED POWDER (2 ML VIAL x 5 MG)
ACTIVE HALF-LIFE: APPROX. 1 HOUR
DOSAGE: 100–500 MCG/DAY (RESEARCH USE)
ACNE: NO
WATER RETENTION: NO
HIGH BLOOD PRESSURE (HBP): NO
HEPATOTOXICITY: NONE
AROMATIZATION: NO
MANUFACTURER: PEPTIDE HUBS
Kisspeptin-10 5 mg – Peptide Hubs
Kisspeptin-10 is a short-chain synthetic analog of the natural kisspeptin protein, a key regulator of the hypothalamic-pituitary-gonadal (HPG) axis. It plays a central role in initiating the secretion of gonadotropin-releasing hormone (GnRH), which stimulates luteinizing hormone (LH) and follicle-stimulating hormone (FSH). Peptide Hubs offers Kisspeptin-10 in a 5 mg lyophilized format, designed for high-purity hormonal and fertility research.
Mechanism of Action
Kisspeptin binds to the GPR54 receptor, triggering a cascade that stimulates GnRH neurons in the hypothalamus. This activation enhances LH and FSH release from the pituitary gland, driving downstream testosterone or estrogen production. It is commonly studied in the context of fertility, hypogonadism, puberty regulation, and HPG axis reactivation. For an overview of kisspeptin's endocrinological role, consult this NIH review on Kisspeptin signaling.
Primary Research Applications
- GnRH and LH/FSH stimulation in fertility models
- Post-cycle therapy (PCT) and testosterone recovery
- Hypogonadism and puberty regulation studies
- Neuroendocrine function and reproductive axis mapping
Kisspeptin-10 may be stacked with Gonadorelin for comparative pituitary stimulation, or combined with HCG 2500 IU to evaluate endogenous testosterone reactivation. Researchers may also study synergies with GHRP-6 and DSIP for hormone–sleep axis modulation.
Suggested Experimental Use
- Dosage: 100–500 mcg per day (split into 1–2 doses)
- Administration: Subcutaneous injection
- Cycle Duration: 7–21 days depending on model protocol
Stacking Combinations
- Gonadorelin – to compare central vs direct LH/FSH stimulation
- FOX04-DRI – for aging-related HPG suppression models
- Chonluten – to support immune function during hormone rebalancing
- B7-33 – for tissue remodeling support in hormonal recovery studies
Safety & Legal Status
Kisspeptin-10 is for laboratory research use only and is not FDA-approved. Preclinical models show favorable safety with no aromatization, androgenicity, or hepatotoxicity. Its use is confined to academic and experimental settings. For ongoing research and clinical trials, refer to ClinicalTrials.gov.
Frequently Asked Questions
What is Kisspeptin-10 used for in research?
Kisspeptin-10 is used to stimulate GnRH and LH/FSH release in studies related to fertility, puberty, and testosterone recovery models.
How does Kisspeptin-10 differ from HCG or Clomid?
Unlike HCG, which mimics LH, Kisspeptin-10 stimulates the brain's GnRH production upstream. Clomid blocks estrogen receptors, while Kisspeptin works directly on GnRH neurons.
Can Kisspeptin-10 be used in post-cycle therapy (PCT)?
Yes. In research, Kisspeptin-10 is studied for its ability to restart the HPG axis and restore LH/FSH levels after androgen suppression or steroid cycles.
Is Kisspeptin-10 approved for human use?
No. Kisspeptin-10 is not FDA-approved and is sold strictly for laboratory research and experimental hormone-related studies.
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